Butylene Glycol Vs Propylene Glycol Allergy. [1][2] These characteristics make glycol ethers essential in

[1][2] These characteristics make glycol ethers essential in . Understand the potential risks including skin irritation, allergic reactions, respiratory issues, eye irritation, toxicity, environm Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Feb 20, 2019 · Learn about butylene glycol, a popular ingredient in cosmetics and skin care products that's generally safe for most people to use. however, given that glycols are in the majority of skincare products, im curious whether others who are allergic to propylene glycol have any experience with tolerating other glycols (caprylyl glycol, butylene glycol, etc)? im wondering if itd be wise to continue avoiding these or if they’re different enough that it likely won’t be an issue. I have tried using solely DNS products from my dermatologist that don't have these. true i’m still unsure about propylene glycol, but pentylene and butylene glycol both break me out in pretty nasty ways. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. In glycols, the alcohol groups are attached to different carbons. My question is how to test for a potential allergic response to macrogols/polyethylene glycol/propylene glycol. Sep 10, 2024 · Our comprehensive guide to cosmetic ingredients to avoid helps you find and purchase safe, healthy products for you and your family. 36, 40 especially if the reaction isrelatively weak. It has the potential to cause allergic contact dermatitis in some individuals Aug 17, 2023 · Background: Propylene glycol (PG) and butylene glycol (BG) are not known to be cross-reactors. 3 Feb 1, 2023 · Propylene glycol (PG) has widespread use in pharmaceuticals, cosmetics, fragrances and personal care products. Solvent, a solvent used to replace Propylene Glycol and Butylene Glycol can help retain water well. Sooo I'm VERY allergic to propylene glycol. 8 In the Certainly, a significant number of May 27, 2021 · Butylene glycol is a colorless chemical ingredient used in self-care products as a conditioner or moisturizer. Patch testing revealed an allergy to propylene glycol, but no reaction to butylene glycol or minoxidil. Propylene glycol is a small, synthetic alcohol found in a number of products including some personal care items, topical medications, foods, and electronic cigarettes. I find the other glycols not so bad unless they are high up the ingredients list, if propylene or pentylene is in the top 4-5 ingredients I tend to get a reaction. Radiant Cream Color: Water, Stearyl Alcohol, Propylene Glycol, Ethanolamine, Cetyl Alcohol, Ceteareth-25, Cocamide Mea, Ceteth-2, Polyquaternium-6, Argania Spinosa Kernel Oil, Hydrolyzed Keratin, Panax Ginseng Root Extract, Dimethicone, Palmitic Acid, Ascorbic Acid, EDTA, Sodium Hydrosulfite, Sodium Sulfite, Butylene Glycol, Toluene-2,5-Diamine Soothing Cleanser: Water / Aqua / Eau, Squalane, Glycerin, Butylene Glycol, Phenyl Trimethicone, Ammonium Acryloyldimethyltaurate / VP Copolymer, Avena Sativa (Oat) Kernel Extract, Cucumis Sativus (Cucumber) Fruit Extract, Hordeum Vulgare (Barley) Extract / Extrait D'Orge, Sucrose Stearate, Sea Whip Extract, Cholesterol, Helianthus Annuus Can someone explain to me the difference between propylene/butylene/pentylene and caprylyl glycol? [Misc] Miscellaneous Propanediol vs. It is unlikely to cause any worrying problems if you eat something that contains propylene glycol, however potentially it could cause a flare of eczema/ itchy skin. We would like to show you a description here but the site won’t allow us. Apr 4, 2024 · Ingredients Uncovered Polyethylene Glycol (PEG) vs. 1,3-butylene glycol or 1,3-butanediol have two alcohol groups (-OH) attached to the first and third carbon atoms of a four-carbon atom chain. Aug 12, 2021 · There are four structural isomers of butylene glycol, but there are two common structural isomers of butylene glycol; 1,3-butylene glycol and 2,3-butylene glycol. PG is a useful, flexible multipurpose chemical. Diols with 1,2-substitution regiochem-istry (e. Glycol vs. The usual problem with propylene glycol allergy is with itchy skin at the site of contact with a substance containing this chemical. Dec 14, 2023 · Butylene glycol and the glycols with a higher carbon chain are used however as preservative boosters and usually when you use them, you can reduce the preservative concentration (this all needs to be backed up by challenge testing). There's a foundation I'm looking at buying and I noticed it has dipropylene glycol. No propylene or butylene glycol, and pentylene glycol is at least halfway down the list of ingredients. Objectives: The aim of this study was to determine whether PG and BG demonstrate cross-reactivity. Pentylene Glycol is known for its superior hydrating properties, gentle nature, and preservative properties, making it a versatile ingredient for a wide range of skincare products. It is mainly used in leave-on and rinse-off formulations. The other 12 are arachidyl glycol, cetyl glycol, hexacosyl glycol, lauryl glycol, myristyl glycol, octacosanyl glycol, stearyl glycol, decylene glycol, 1,2-butanediol, C14-18 glycol, C18-30 glycol, and C20-30 glycol. In a variety of consum Apr 6, 2018 · So when you’re selecting your cosmetics, don’t avoid Glycol entirely, just be sure that the product your choosing doesn’t contain harmful Glycols like Propylene Glycol or Butylene Glycol. 2-10 Almost all of these previously-reviewed diols were assessed to be safe as used; Propylene Glycol (i. 20004 propylene glycol Your patch test result indicates that you have a contact allergy to propylene glycol. It is a water soluble, colorless liquid. I suspect I might have an allergy to propylene glycol (I'm getting allergy tested in a few weeks). For anyone worried about this, it may be worth asking the company which form of propanediol they use in their products. Guidelines for patients sensitive to propylene glycol are discussed. I avoid butylene glycol as I think that’s the major cause of my hives and dermatitis. The remaining 12 ingredients are not reported in the current use. This means that it will have different properties to glycerine because of this difference in structure. Polyethylene glycol (PEG) and propylene glycol (PG) are two widely used synthetic compounds with a range of applications spanning from pharmaceuticals and cosmetics to industrial processes. PG is not classified as hazardous under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) but poses an intriguing scientific and regulatory conundrum with respect to allergic contact dermatitis (ACD), the uncertainty being whether and to what extent PG I suspect I might have an allergy to propylene glycol (I'm getting allergy tested in a few weeks). (water-binding, humectant) and help resist pathogens. However, it is important to note that propylene glycol has a higher potential for toxicity compared to butylene glycol. Polyethylene glycol Polyethylene glycol (PEG; / ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, - ˈɛθɪl -, - ˌkɔːl /) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. Oct 29, 2024 · Palep adds that propanediol is derived from corn, while propylene glycol is derived from petrochemicals. Unfortunately, they have another more dangerous sister. Methods: This is a retrospective chart review of 893 Aug 25, 2023 · In this article, we discuss butylene glycol in further detail, including its uses, benefits, and side effects. Moisturization performance vs. The literature on propylene glycol is reviewed, with particular attention to the nature of these adverse cutaneous effects. Learn its key uses, hydrating benefits, and potential side effects for informed skin choices. Propylene and butylene glycols are found in lots of personal care products, especially in skincare. Mar 26, 2025 · Ethylene Glycol vs Propylene Glycol: Learn how they differ, their safety profiles, and which one is best for skincare and cosmetics. e. May 27, 2021 · Moisturizers Glycols and particularly propylene glycol, butylene glycol and pentylene glycol have hygroscopic features or in other words, they absorb water and retain it through hydrogen bridges. OK, so if I know what to avoid, what do I use instead? There are many different types of compounds that belong to this family, such as butylene glycol, polyethylene glycol, ethylene glycol, and more. petroleum-based glycols In two independent tests conducted between Zemea® propanediol and petroleum-based glycols, measurements with a Corneometer 825 PC® (Courage + Khazaka) revealed that Zemea® propanediol was more eficient than either PG or butylene glycol (BG) at moisturizing the skin at a 5% use level. Jun 11, 2023 · Sometimes, butylene glycol is mistaken for propylene glycol, which is not as safe. In rare cases, high concentrations of propylene glycol may cause adverse effects such as skin irritation, allergic reactions, or respiratory issues. Learn how to avoid Propylene Glycol in your daily life. Humectants attract and retain moisture, while moisturizers help seal your skin’s surface so the Mar 10, 2024 · Glycol ethers have been a versatile and essential solvent group widely utilized in industrial and commercial settings since their initial development in the 1930s. This is one of the first ingredients IN EVERYTHING - shampoo, the best foundations, cleansers, deodorant, toothpaste, even donuts. Glycols in chemistry are ingredients that contain two OH (alcohol) groups. MeSH terms Cosmetics / adverse effects* Cross Reactions Dermatitis, Allergic Contact / etiology* Dermatitis, Allergic Contact / immunology Humans Propylene Glycols / adverse effects* A Cosmetic Ingredient Review (CIR) final safety assess-ment on propylene glycol (PG), short-chain 1,2-glycol, and polypropylene glycols (PPGs) was published in 1994. Diet affects skin strongly too. com University of Illinois Urbana-Champaign North Shore Center for Medical Aesthetics Northbrook, IL Polyethylene glycol (PEG) and propylene glycol (PG) are two widely used synthetic compounds with a range of applications spanning from pharmaceuticals and cosmetics to industrial processes. Feb 26, 2025 · Discover the ins and outs of PGPR allergy - its symptoms, diagnosis, and effective treatments like sublingual immunotherapy. Butylene Glycol vs Propylene Glycol Butylene glycol is often compared to propylene glycol, and that’s because the two are used in similar products and both derived from petroleum. Propylene Glycol What's the Difference? Polyethylene Glycol (PEG) and Propylene Glycol (PG) are both types of glycols commonly used in various industries. Restore & Renew Face & Neck Multi Action Serum: Aqua (Water), Dimethicone, Glycerin, Butylene Glycol, Aluminum Starch Octenylsuccinate, Isononyl Isononanoate, Gluconolactone, Dimethicone Crosspolymer, Cetearyl Alcohol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Phenoxyethanol, 3-O-Ethyl Ascorbic Acid, Pentylene Glycol, Polysorbate 20 10 votes, 27 comments. Again, this depends on your reaction to them. Dec 10, 2025 · And although it’s pretty uncommon, there have been some reports of allergic contact dermatitis reactions to butylene glycol. Jun 26, 2015 · Propylene Glycol – Zemea® has replaced propylene glycol usage in most formulations. However, they have distinct differences. Consider the Although propylene glycol is a ubiquitous ingredient in hair care products, there has been some debate about its use due to possible health hazards. Although it is well suited for this purpose, it is capable of producing both primary irritant skin reactions and allergic sensitization. Sep 29, 2021 · Caprylyl glycol works as a humectant, which means it helps hydrate your skin, King explains. Propylene glycol contains 3 carbon atoms, while butylene glycol is a little larger and contains 4 carbon atoms. Apr 9, 2025 · FAQs Is propylene glycol safe for all hair types? Yes, propylene glycol is generally safe for all hair types. Jun 6, 2024 · IntroductionWhat makes polyethylene glycol vs propylene glycol different, and how does this affect their use in products you use every day? From safety to applications, this comparison addresses the key distinctions that inform their roles in various industries. Explore how butylene glycol enhances skincare in 2025. We will explain what propylene glycol is, why it is used in hair products, any potential hazards or advantages, and possible substitute ingredients. But some experts caution that it might cause allergies although it's generally safe Dec 26, 2023 · Polyethylene glycol is a polymer used in laxatives and lubricants, while propylene glycol is a small organic alcohol used in food and cosmetics. Propylene glycol is 1,2-propanediol, but there is also 1,3-propanediol that doesn't have the same sensitizing effects and is often used as a replacement for propylene glycol. Based on the current information, 4 of the16 ingredients reviewed in this safety assessment, are being used in personal care products: caprylyl glycol, pentylene glycol, 1,2-hexanediol, and C15-18 glycol. Despite these patch testing results, she was unable to tolerate the compounded formulation because of continued scaling and pruritus at the application site. How do you wrap your mind around it all? Brand names and trade names require research, but chemical names and families (related chemicals) are something you can learn. allergy to polyethylene glycol, propylene glycol, ethylene & butylene glycols Product Recommendations – Or Not? Tips to Surviving a Glycol Allergy As someone with multiple allergies to chemical ingredients and scents, I am always looking for products that are safe to use. Glycerin-containing cosmetic products improve the skin moisture. In 2010, the Expert Panel issued an amended final safety assessment on PG, tripropylene glycol, and PPGs and Jan 23, 2022 · Identify coconut derivatives that could cause an allergic reaction with this ultimate list of coconut derivatives in skin care. It can act as a preservative booster. Consider the Jan 19, 2018 · Propylene glycol (PG) has been a commercial product in the United States since the 1930s. , 1,2-Propanediol) was deemed to be safe as used when formulated to be non Jun 11, 2023 · Sometimes, butylene glycol is mistaken for propylene glycol, which is not as safe. it’s not a perfect compromise, but most “natural” brands don’t use glycols, and most of them will have a few products for sensitive skin that don’t contain essential oils. PG is not classified as hazardous under the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) but poses an intriguing scientific and regulatory conundrum with respect to allergic contact dermatitis (ACD), the uncertainty being whether and to what extent PG Aug 17, 2024 · The present study aims to investigate the current trends in replacing conventional preservatives with multifunctional ingredients with antimicrobial properties for preservation of cosmetics for however, given that glycols are in the majority of skincare products, im curious whether others who are allergic to propylene glycol have any experience with tolerating other glycols (caprylyl glycol, butylene glycol, etc)? im wondering if itd be wise to continue avoiding these or if they’re different enough that it likely won’t be an issue. However, no large-scale studies have assessed the cross-reactivity rate (CRR) between these 2 structurally and functionally similar compounds. Ethylene glycol. Jun 21, 2024 · Find out what you need to know about propylene glycol in foods. Learn practical ways to avoid exposure in food and skincare products. Though both alcohols, propylene glycol is more irritating and has a higher potential of causing contact dermatitis, cosmetic chemist Ron Robinson explained to Byrdie. Although propylene glycol is determined to be safe in skincare and cosmetics, propanediol is commonly used as an alternative to propylene glycol for those who want products that don't contain petroleum -based glycols. Feb 1, 2023 · Propylene glycol (PG) has widespread use in pharmaceuticals, cosmetics, fragrances and personal care products. Aug 17, 2023 · Background: Propylene glycol (PG) and butylene glycol (BG) are not known to be cross-reactors. I hate DE’s fear mongering and basically how they victim customers (where they say if their products don’t work for you you must be doing something wrong!) but damn does this stuff calm my face down a lot. Discover what it is, its uses, and the risk it poses to your health. , 1,2-Butanediol) have been reviewed previously by the Panel, and the conclusion for each is summarized in Table 2. Propylene Glycol They’re both derived from petroleum products and have similar uses in skincare. Jun 30, 2017 · For example, a person who has an allergic reaction to propylene glycol could also react to polyethylene glycol, butylene glycol, or any number of other glycols. Butylene Glycol is a conditioning agent that covers your skin and hair. It acts as a humectant. glycerin: main differences The main difference between glycol and glycerine lies in its chemical composition. 0%. 5% of the studied population. Propylene Glycol: Distinguishing Between Similar Ingredients Although propylene glycol and propanediol are both useful components in cosmetics and personal care products, their origins, skin compatibility, and environmental effects are very different. Explore the comprehensive list of negative effects of Propylene Glycol (PG) and Butylene Glycol in personal care products. My skin was ok at the time. Because of this reason, butylene is used as a substitute for propylene in a lot of skincare products. Feb 26, 2025 · Discover the signs of propylene glycol allergy, how it's diagnosed, and effective treatment options. Allergy to Polyethylene Glycols (PEGs), also known as macrogols, are compounds widely used in medicines, cosmetics and household products. PEG is a polymer made up of repeating ethylene glycol units, while PG is a smaller molecule composed of propylene glycol units. Confusingly, the names “propylene glycol” and “butylene glycol” can refer to several slightly dif Propylene glycol is a small, synthetic alcohol found in a number of products including some personal care items, topical medications, foods, and electronic cigarettes. LETTERS Contact Allergy to Propylene Glycol and Cross-Reactions Scheman, Andrew MD; Roszko, Karolina BS Author Information Department of Dermatology Northwestern University Feinberg School of Medicine Chicago, IL patchtest@scheman. it is possible to avoid though. Propylene glycol may be non-irritating to the skin, see section Allergic reaction below for details on allergic reactions. Butylene Glycol: Helps to boost hair’s moisture while providing a silky, smooth texture Sodium Cocoylamino Acids: Restores shine and smoothes for healthier-looking hair Propylene glycol sometimes causes irritation to the skin while, butylene glycol is safe and has more hydrating qualities in it. Jun 2, 2021 · Is the propylene glycol in your hair care products making you itch? Although the French Chemist Charles-Adolphe Wurtz didn’t identify propylene glycol (PG) until 1859, today it is a widely used chemical in everything from the foods we eat to the cosmetics and hair care products we use. Dipropylene glycol is a colorless, nearly odorless liquid with a high boiling point and low toxicity. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. If you don't like propanediol, other products may use alcohols or glycolic acid to help penetration. Eric Macy for assistance with the response. g. Polyethylene Glycol vs. C. [53] Undiluted propylene glycol is minimally irritating to the eye, producing slight transient conjunctivitis; the eye recovers after the exposure is removed. Even studies on make-up products and their ingredients are full of bias and agendas who do you think does most of these studies? Oct 11, 2012 · Caprylyl glycol and pentylene glycol are also used as preservatives. Is it similar to dipropylene glycol or completely different? I Googled the differences between the two but I'm still a little confused. This ingredient is harmful and should not be used in 555 13th Street, NW, Suite 300W Washington, D. The patient does not have any known allergies or PMH. Does propylene glycol cause hair damage? The suggested concentration does not hurt hair when used as Propylene glycol is a commonly used vehicle for topical preparations. Glycol ethers possess a unique combination of physical properties, including high solvency, low evaporation rates, and miscibility with both water and organic substances. Glycol contains one more oxygen atom than glycerine does. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Ataman Kimya Synonyms: Butylene Glycol; 1,3-Butanediol; 2-Butoxyethanol, butyl cellosolve, butyl glycol, ethylene glycol monobutyl ether, Dowanol; Cas No: 111-76-2; 2-butoxyethanol Butylene glycol is an organic alcohol used as a solvent and conditioning agent in cosmetics industry. Even though they sound similar, they’re not the same thing. But patch testing is recommended for individuals who have sensitive scalps or allergies before adding it to their haircare routine. Natural Based Humectants Glycerin Pentylene Glycol (MinaCare® Pentiol Green by Minasolve) 1,3 Butylene Glycol Propanediol (Zemea® by Tate and Lyle) Sodium PCA (AJIDEW® NL-50 by Ajinomoto) Sodium-L-Lactate (PURASAL® S/HQ60 by Corbion Purac) Mar 14, 2024 · So, it’s time to find out: what is butylene glycol used for in skincare products, is it safe to put this ingredient on my skin, and is it comedogenic? In short, butylene glycol is a chemical compound commonly used as an alternative to propylene glycol or glycerol in skincare products. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. We also explore how butylene glycol differs from propylene glycol. Among the studies l sted, the percentage of positive responses ing, particularly with propylene glycol, is reliably judged torepresent allergy ranges from zero to differentiating a irritant from an allergic response, 12. It has the potential to cause allergic contact dermatitis in some individuals I avoid butylene glycol as I think that’s the major cause of my hives and dermatitis. Here’s the science behind whether or not they’re safe. Aug 21, 2012 · Water, Cyclopentasiloxane, Stearic Acid, Ethylhexyl Palmitate, Glycerin, Acrylates Crosspolymer, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide 3, Glyceryl Stearate, Glycyrrhiza Glabra Root Extract (licorice), Phytonadione, Aloe Vera (Aloe Barbadensis) Extract, Limmanthes Alba (Meadowfoam) Seed Extract Jul 28, 2021 · Butylene Glycol vs. Propylene Glycol (PG) in Beauty Products By Petra Nakashian April 4, 2024 When you look at the ingredients in your beauty products, you’ll often see things like Polyethylene Glycol (PEG) and Propylene Glycol (PG). It became a very common product in air fresheners when a researcher’s work indicated it could sterilize air. 1The Expert Panel concluded that PG and PPGs are safe for use in cosmetic products at concentrations up to 50. My question was allergy to “Propylene Glycol “not to “polyethylene glycol”. This guide cuts through the complexity, giving you a clear understanding of… Whole Milk, Sugar, Annatto color, Natural Flavor, Propylene Glycol, Natural Turmeric Color, Sodium Benzoate, Polysorbate 80, Znthan Gum, Citric Acid, Vitamin D3 I thought possible evaluation for Annatto allergies but Propylene Glycol was the common between the two. Would this be performed through skin testing? Is there any protocol in place to follow for this type of allergy? I asked Dr. Propylene glycol however, tends to be more irritating. In conclusion, Pentylene Glycol and Propanediol are both valuable ingredients in skincare and cosmetic products, each with its own unique attributes and benefits.

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